Results 1-15 of 15

Issue DateTitleTypeAuthor(s)
12-Mar-2021Fulltext availableOpen AccessDigital twins for tissue culture techniques : concepts, expectations, and state of the artArticleMöller, Johannes ; Pörtner, Ralf  
213-Jan-2021Fulltext availableOpen AccessModel-based workflow for scale-up of process strategies developed in miniaturized bioreactor systemsArticleArndt, Lukas ; Wiegmann, Vincent ; Kuchemüller, Kim Beatrice ; Baganz, Frank ; Pörtner, Ralf  ; Möller, Johannes 
32021Digital Twins and Their Role in Model-Assisted Design of ExperimentsChapter (Book)Kuchemüller, Kim Beatrice ; Pörtner, Ralf  ; Möller, Johannes 
419-Oct-2020Fulltext availableOpen AccessNMPC-based workflow for simultaneous process and model development applied to a fed-batch process for recombinant C. glutamicumArticleLevermann, Philipp ; Freiberger, Fabian ; Katha, Uma ; Zaun, Henning ; Möller, Johannes ; Hass, Volker C. ; Schoop, Karl Michael ; Kuballa, Jürgen ; Pörtner, Ralf  
528-Sep-2020Fulltext availableOpen AccessRegulation of pyruvate dehydrogenase complex related to lactate switch in CHO cellsArticleMöller, Johannes ; Bhat, Krathika ; Guhl, Lotta ; Pörtner, Ralf  ; Jandt, Uwe ; Zeng, An-Ping  
64-Mar-2020Fulltext availableOpen AccessModel uncertainty-based evaluation of process strategies during scale-up of biopharmaceutical processesArticleMöller, Johannes ; Hernández Rodríguez, Tanja ; Müller, Jan ; Arndt, Lukas ; Kuchemüller, Kim Beatrice ; Frahm, Björn ; Eibl, Regine ; Eibl, Dieter ; Pörtner, Ralf  
74-Mar-2020Fulltext availableOpen AccessQuantification of the dynamics of population heterogeneities in CHO cultures with stably integrated fluorescent markersArticleMöller, Johannes ; Rosenberg, Marcel ; Riecken, Kristoffer ; Pörtner, Ralf  ; Zeng, An-Ping  ; Jandt, Uwe 
82020Modeling and experimental analysis of antibody-producing cell culture processes : from metabolism over population to design and scale-upThesisMöller, Johannes 
92020Estimation of process model parametersChapter (Book)Deppe, Sahar ; Frahm, Björn ; Hass, Volker C. ; Hernández Rodríguez, Tanja ; Kuchemüller, Kim Beatrice ; Möller, Johannes ; Pörtner, Ralf  
102020Efficient optimization of process strategies with model-assisted design of experimentsChapter (Book)Kuchemüller, Kim Beatrice ; Pörtner, Ralf  ; Möller, Johannes 
112020Near-physiological cell cycle synchronization with countercurrent centrifugal elutriationChapter (Book)Möller, Johannes ; Korte, Katrin ; Pörtner, Ralf  ; Zeng, An-Ping  ; Jandt, Uwe 
12May-2019Model-assisted Design of Experiments as a concept for knowledge-based bioprocess developmentArticleMöller, Johannes ; Kuchemüller, Kim Beatrice ; Steinmetz, Tobias ; Koopmann, Kirsten ; Pörtner, Ralf  
132019Fulltext availableOpen AccessProcess-induced cell cycle oscillations in CHO cultures: Online monitoring and model-based investigationArticleMöller, Johannes ; Bhat, Krathika ; Riecken, Kristoffer ; Pörtner, Ralf  ; Zeng, An-Ping  ; Jandt, Uwe 
14Dec-2018Model-based tools for optimal experiments in bioprocess engineeringArticleAbt, Vinzenz ; Barz, Tilman ; Cruz, Nicolay ; Herwig, Christoph ; Kroll, Paul ; Möller, Johannes ; Pörtner, Ralf  ; Schenkendorf, René 
15Dec-2018Model-based identification of cell-cycle-dependent metabolism and putative autocrine effects in antibody producing CHO cell cultureArticleMöller, Johannes ; Korte, Katrin ; Pörtner, Ralf  ; Zeng, An-Ping  ; Jandt, Uwe