Microbial production of diols as platform chemicals : recent progresses

Publikationstyp
Journal Article
Date Issued
2011
Sprache
English
Author(s)
Zeng, An-Ping  orcid-logo
Sabra, Wael  
Institut
Bioprozess- und Biosystemtechnik V-1  
TORE-URI
http://hdl.handle.net/11420/12459
Journal
Current opinion in biotechnology  
Volume
22
Issue
6
Start Page
749
End Page
757
Citation
Current Opinion in Biotechnology 22 (6): 749-757 (2011)
Publisher DOI
10.1016/j.copbio.2011.05.005
Scopus ID
2-s2.0-82755161073
PubMed ID
21646010
Publisher
Elsevier Science
Diols are chemicals with two hydroxyl groups which have a wide range of appealing applications as chemicals and fuels. In particular, four diol compounds, namely 1,3-propanediol (1,3-PDO), 1,2-propanediol (1,2-PDO), 2,3-butanediol (2,3-BDO) and 1,4-butanediol (1,4-BDO) can be biotechnologically produced by direct microbial bioconversion of renewable materials. These diols are considered as platform green chemicals. We review and discuss here the recent development in the microbial production of these diols, especially regarding the engineering of production strains and optimization of the fermentation processes.
DDC Class
570: Biowissenschaften, Biologie