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Entwicklung eines enzymatischen und synthetischen Produktionsverfahrens für 1,3-Propandiol aus Glycerol
Citation Link: https://doi.org/10.15480/882.1175
Other Titles
Development of an enzymatic and synthetic production process for 1,3-propanediol from glycerol
Publikationstyp
Doctoral Thesis
Date Issued
2014
Sprache
German
Author(s)
Advisor
Title Granting Institution
Technische Universität Hamburg
Place of Title Granting Institution
Hamburg
Examination Date
2014-05-23
Institut
TORE-DOI
In the present work the feasibility of engineering an enzymatic in vitro production process for 1,3-propanediol (1,3-PDO) from glycerol was demonstrated. In this novel bioprocess, a very high production yield of about 0.95 mol 1,3-PDO/mol glycerol was reached. The bottleneck of the process regarding costs and productivity is considered to be mainly related to the inactivation of glycerol dehydratase through its mechanism-based suicide-effect.
Subjects
Propandiol
Glycerol
enzymatisch
Produktionsprozess
propanediol
glycerol
enzymatic
production process
DDC Class
620: Ingenieurwissenschaften
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