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  4. Synthetic pathways and processes for effective production of 5-hydroxytryptophan and serotonin from glucose in Escherichia coli
 
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Synthetic pathways and processes for effective production of 5-hydroxytryptophan and serotonin from glucose in Escherichia coli

Citation Link: https://doi.org/10.15480/882.2123
Publikationstyp
Journal Article
Date Issued
2018-03-15
Sprache
English
Author(s)
Mora Villalobos, José Aníbal  
Zeng, An-Ping  orcid-logo
Institut
Bioprozess- und Biosystemtechnik V-1  
TORE-DOI
10.15480/882.2123
TORE-URI
http://hdl.handle.net/11420/2206
Journal
Journal of biological engineering  
Volume
12
Issue
1
Start Page
Art.-Nr. 3
Citation
Journal of biological engineering 1 (12): 3- (2018)
Publisher DOI
10.1186/s13036-018-0094-7
Scopus ID
2-s2.0-85043753914
Publisher
BioMed Central ; Springer
Tryptophan derivatives such as 5-hydroxytryptophan (5HTP) and serotonin are valuable molecules with pharmaceutical interest. 5HTP is presently mainly obtained by extraction from the plant Griffonia simplicifolia and serotonin is produced by chemical synthesis. A simple biotechnological method for the production of these compounds is desired.
Subjects
5-hydroxytryptophan
Aromatic amino acid hydroxylase
Protein engineering
Serotonin
Synthetic pathway
DDC Class
570: Biowissenschaften, Biologie
620: Ingenieurwissenschaften
Funding(s)
Open Access Publizieren 2018 - 2019 / TU Hamburg  
Lizenz
https://creativecommons.org/licenses/by/4.0/
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