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Hybrid Alginate-Based Cryogels for Life Science Applications
Publikationstyp
Journal Article
Date Issued
2016-11-01
Sprache
English
Institut
TORE-URI
Journal
Volume
88
Issue
11
Start Page
1770
End Page
1778
Citation
Chemie-Ingenieur-Technik 11 (88): 1770-1778 (2016-11-01)
Publisher DOI
Scopus ID
This work presents a novel route toward porous scaffolds for tissue engineering and regenerative medicine (TERM) applications. Hybrid cryogels with gelatin, gellan gum, carboxymethylcellulose, and lignin were prepared by a two-step process. Textural properties of the cryogels were analyzed by SEM and micro-computed tomography. The results indicated that rapid freezing retained sample shape and yielded macroporous materials. The mechanical properties of the cryogels were characterized in compression mode. Cytotoxicity studies indicated that the hybrid-alginate cryogels did not present cytotoxicity and have the potential to be used in TERM.
Subjects
Alginate
Cryogel
Freeze-drying