Präklinische Testung - klinische Anwendung - Schadensanalyse [Preclinical testing - clinical application - risk assessment : example using hip arthroplasty]

Preclinical testing - clinical application: Total hip arthroplasty has become one of the most successful procedures in orthopedics. This has been made possible through continuous improvement of the implant systems and materials accompanied by an improvement in preclinical testing and the legal framework. A further improvement in results can only be achieved if the two other decisive factors for the success of an operation are also included: intensive education and training of the surgeons combined with education and awareness of the patients. Risk assessment: The introduction of new concepts always bears the risk of new unforeseen failure mechanisms, which cannot always be prevented by established preclinical testing. This requires the careful introduction of new concepts into clinical application, combined with a standardized failure analysis, in order to reduce the number of problem cases in the worst case situation. © 2013 Springer-Verlag Berlin Heidelberg.

Schlagworte

Clinical studies

Device failure

Preclincial testing

Prostheses and implants

Technological innovations

DDC Class

600: Technik

610: Medizin

620: Ingenieurwissenschaften

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Präklinische Testung - klinische Anwendung - Schadensanalyse [Preclinical testing - clinical application - risk assessment : example using hip arthroplasty]