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Microfluidic device for the continuous preparation of eukaryotic cells for metabolic analysis
Publikationstyp
Conference Paper
Date Issued
2013
Sprache
English
TORE-URI
Start Page
259
End Page
262
Article Number
6474227
Citation
2013 IEEE 26th International Conference on Micro Electro Mechanical Systems (MEMS 2013) : Taipei, Taiwan, 20 - 24 January 2013 / [IEEE Robotics and Automation Society]. - Piscataway, NJ : IEEE, 2013. - Art.-Nr. 6474227 i.e. Seite 259-262
Contribution to Conference
Publisher DOI
Scopus ID
Publisher
IEEE
A novel lab-on-a-chip is presented for the high-throughput preparation of mammalian cell samples. The microfluidic chip consists of two temperature zones and five functional modules with a total number of four fluidic inlet and three outlet channels for sample collection. The key modules of the chip are a rapid split-and-recombine micromixer for biological system perturbation, a chaotic advection 'stirred' incubation channel for lowered residence time distribution, and a spiral channel for efficient particle separation and media exchange. The passive chip is suitable for dynamic pulse experiments for metabolic analyses in cell compartments. © 2013 IEEE.
DDC Class
570: Biowissenschaften, Biologie
600: Technik
620: Ingenieurwissenschaften
More Funding Information
Deutschland, Bundesministerium für Bildung und Forschung (BMBF)