Reactive Separations for In Situ Product Removal of Enzymatic Reactions: A Review

Publikationstyp
Journal Article
Date Issued
2019-11-01
Sprache
English
Author(s)
Fellechner, Oliver 
Blatkiewicz, Michał  
Smirnova, Irina  orcid-logo
Institut
Thermische Verfahrenstechnik V-8  
TORE-URI
http://hdl.handle.net/11420/3720
Journal
Chemie - Ingenieur - Technik  
Volume
91
Issue
11
Start Page
1522
End Page
1543
Citation
Chemie-Ingenieur-Technik 11 (91): 1522-1543 (2019-11-01)
Publisher DOI
10.1002/cite.201900027
Scopus ID
2-s2.0-85074063862
The topic of integrating enzymatic reactions with in situ product removal is addressed. Different integrated reactive separations structured accordingly to the corresponding unit operations, i.e., reactive distillation, reactive chromatography, reactive crystallization, and extractive biocatalysis, are discussed. Special attention is given to their realization with homogenous and heterogeneous biocatalysis. Various enzyme immobilization techniques are presented and distinct strategies for installation of heterogeneous catalysts into process equipment are discussed.
Subjects
Extractive biocatalysis
Extractive bioconversion
In situ product removal
Process intensification
Reactive crystallization
Reactive distillation