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The Brain–Bladder Axis in Tissue Growth and Remodelling
Publikationstyp
Book
Publikationsdatum
2021
Sprache
English
Author
Miftahof, Roustem
First published in
Citation
in: IPEM–IOP Series in Physics and Engineering in Medicine and Biology. IOP Publishing Ltd (2021)
Publisher DOI
Publisher
IOP Publishing
ISBN
978-0-7503-3567-6
978-0-7503-3565-2
Applying the general deterministic approach of systems computational biology, the monograph considers questions related to the biomechanics of the human urinary bladder in conjunction with the peripheral and central nervous systems. The step-by-step development of mathematical models of separate structural elements and their assembly into a unique self-regulatory system offers, for the first time, a holistic overview and allows the investigation of the dynamics of the lower urinary tract system at its hierarchical levels. This book provides a coherent description and explanation for intertwined intracellular pathways in terms of spatiotemporal, whole body, tractable representations which are supported by numerous computational simulations.