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Protein engineering approaches to chemical biotechnology
Publikationstyp
Review Article
Date Issued
2016-12-01
Sprache
English
Author(s)
Institut
TORE-URI
Journal
Start Page
198
End Page
205
Citation
Current Opinion in Biotechnology (42): 198-205 (2016-12-01)
Publisher DOI
Scopus ID
Protein engineering for the improvement of properties of biocatalysts and for the generation of novel metabolic pathways plays more and more important roles in chemical biotechnology aiming at the production of chemicals from biomass. Although widely used in single-enzyme catalysis process, protein engineering is only being increasingly explored in recent years to achieve more complex in vitro and in vivo biocatalytic processes. This review focuses on major contributions of protein engineering to chemical biotechnology in the field of multi-enzymatic cascade catalysis and metabolic engineering. Especially, we discuss and highlight recent strategies for combining pathway design and protein engineering for the production of novel products.
DDC Class
570: Biowissenschaften, Biologie
600: Technik