Please use this identifier to cite or link to this item: https://doi.org/10.15480/882.1586
DC FieldValueLanguage
dc.contributor.authorLu, Yongtao-
dc.contributor.authorEngelke, Klaus-
dc.contributor.authorGlueer, Claus-C-
dc.contributor.authorMorlock, Michael-
dc.contributor.authorHuber, Gerd-
dc.date.accessioned2018-03-16T09:53:02Z-
dc.date.available2018-03-16T09:53:02Z-
dc.date.issued2014-
dc.identifier.citationProceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine 11 (228): 1208-13-1213 (2014-11)de_DE
dc.identifier.issn0954-4119de_DE
dc.identifier.urihttp://tubdok.tub.tuhh.de/handle/11420/1589-
dc.description.abstractQuantitative computed tomography-based finite element modeling technique is a promising clinical tool for the prediction of bone strength. However, quantitative computed tomography-based finite element models were created from image datasets with different image voxel sizes. The aim of this study was to investigate whether there is an influence of image voxel size on the finite element models. In all 12 thoracolumbar vertebrae were scanned prior to autopsy (in situ) using two different quantitative computed tomography scan protocols, which resulted in image datasets with two different voxel sizes (0.29 × 0.29 × 1.3 mm(3) vs 0.18 × 0.18 × 0.6 mm(3)). Eight of them were scanned after autopsy (in vitro) and the datasets were reconstructed with two voxel sizes (0.32 × 0.32 × 0.6 mm(3) vs. 0.18 × 0.18 × 0.3 mm(3)). Finite element models with cuboid volume of interest extracted from the vertebral cancellous part were created and inhomogeneous bilinear bone properties were defined. Axial compression was simulated. No effect of voxel size was detected on the apparent bone mineral density for both the in situ and in vitro cases. However, the apparent modulus and yield strength showed significant differences in the two voxel size group pairs (in situ and in vitro). In conclusion, the image voxel size may have to be considered when the finite element voxel modeling technique is used in clinical applications.en
dc.language.isoende_DE
dc.relation.ispartofProceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicinede_DE
dc.rightsinfo:eu-repo/semantics/openAccess-
dc.subjectQuantitative computed tomography imagede_DE
dc.subjectfinite elementde_DE
dc.subjectin situde_DE
dc.subjectin vitrode_DE
dc.subjectvertebrade_DE
dc.subjectvoxel sizede_DE
dc.subjectAbsorptiometry, Photonde_DE
dc.subjectAgedde_DE
dc.subjectAged, 80 and overde_DE
dc.subjectBone Densityde_DE
dc.subjectCompressive Strengthde_DE
dc.subjectComputer Simulationde_DE
dc.subjectElastic Modulusde_DE
dc.subjectFemalede_DE
dc.subjectFinite Element Analysisde_DE
dc.subjectHumansde_DE
dc.subjectImaging, Three-Dimensionalde_DE
dc.subjectMiddle Agedde_DE
dc.subjectRadiographic Image Interpretation, Computer-Assistedde_DE
dc.subjectReproducibility of Resultsde_DE
dc.subjectSensitivity and Specificityde_DE
dc.subjectThoracic Vertebraede_DE
dc.subjectTomography, X-Ray Computedde_DE
dc.subjectModels, Biologicalde_DE
dc.subject.ddc610: Medizinde_DE
dc.titleThe effect of in situ/in vitro three-dimensional quantitative computed tomography image voxel size on the finite element model of human vertebral cancellous bonede_DE
dc.typeArticlede_DE
dc.identifier.urnurn:nbn:de:gbv:830-88219911-
dc.identifier.doi10.15480/882.1586-
dc.type.diniarticle-
dc.subject.ddccode610-
dcterms.DCMITypeText-
tuhh.identifier.urnurn:nbn:de:gbv:830-88219911de_DE
tuhh.oai.showtrue-
dc.identifier.hdl11420/1589-
tuhh.abstract.englishQuantitative computed tomography-based finite element modeling technique is a promising clinical tool for the prediction of bone strength. However, quantitative computed tomography-based finite element models were created from image datasets with different image voxel sizes. The aim of this study was to investigate whether there is an influence of image voxel size on the finite element models. In all 12 thoracolumbar vertebrae were scanned prior to autopsy (in situ) using two different quantitative computed tomography scan protocols, which resulted in image datasets with two different voxel sizes (0.29 × 0.29 × 1.3 mm(3) vs 0.18 × 0.18 × 0.6 mm(3)). Eight of them were scanned after autopsy (in vitro) and the datasets were reconstructed with two voxel sizes (0.32 × 0.32 × 0.6 mm(3) vs. 0.18 × 0.18 × 0.3 mm(3)). Finite element models with cuboid volume of interest extracted from the vertebral cancellous part were created and inhomogeneous bilinear bone properties were defined. Axial compression was simulated. No effect of voxel size was detected on the apparent bone mineral density for both the in situ and in vitro cases. However, the apparent modulus and yield strength showed significant differences in the two voxel size group pairs (in situ and in vitro). In conclusion, the image voxel size may have to be considered when the finite element voxel modeling technique is used in clinical applications.de_DE
tuhh.publisher.doi10.1177/0954411914558654-
tuhh.publication.instituteBiomechanik M-3de_DE
tuhh.identifier.doi10.15480/882.1586-
tuhh.type.opus(wissenschaftlicher) Artikelde
tuhh.institute.germanBiomechanik M-3de
tuhh.institute.englishBiomechanik M-3de_DE
tuhh.gvk.hasppnfalse-
tuhh.hasurnfalse-
openaire.rightsinfo:eu-repo/semantics/openAccessde_DE
dc.type.driverarticle-
dc.type.casraiJournal Articleen
tuhh.container.issue11de_DE
tuhh.container.volume228de_DE
tuhh.container.startpage1208de_DE
tuhh.container.endpage1213de_DE
dc.rights.nationallicensetruede_DE
dc.rights.nltextDieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG geförderten) Allianz- bzw. Nationallizenz frei zugänglich. This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.de_DE
item.fulltextWith Fulltext-
item.creatorOrcidLu, Yongtao-
item.creatorOrcidEngelke, Klaus-
item.creatorOrcidGlueer, Claus-C-
item.creatorOrcidMorlock, Michael-
item.creatorOrcidHuber, Gerd-
item.creatorGNDLu, Yongtao-
item.creatorGNDEngelke, Klaus-
item.creatorGNDGlueer, Claus-C-
item.creatorGNDMorlock, Michael-
item.creatorGNDHuber, Gerd-
item.grantfulltextopen-
crisitem.author.deptBiomechanik M-3-
crisitem.author.deptBiomechanik M-3-
crisitem.author.deptBiomechanik M-3-
crisitem.author.orcid0000-0002-8511-6111-
crisitem.author.orcid0000-0001-9875-4123-
crisitem.author.orcid0000-0002-5330-2454-
crisitem.author.orcid0000-0002-9883-3953-
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