Please use this identifier to cite or link to this item: https://doi.org/10.15480/882.2221
DC FieldValueLanguage
dc.contributor.authorWiedorn, Max Oliver-
dc.contributor.authorAwel, Salah-
dc.contributor.authorMorgan, Andrew J.-
dc.contributor.authorAyyer, Kartik-
dc.contributor.authorGevorkov, Yaroslav-
dc.contributor.authorFleckenstein, Holger-
dc.contributor.authorRoth, Nils-
dc.contributor.authorAdriano, Luigi-
dc.contributor.authorBean, Richard-
dc.contributor.authorBeyerlein, Kenneth R.-
dc.contributor.authorChen, Joe-
dc.contributor.authorCoe, Jesse-
dc.contributor.authorCruz-Mazo, Francisco-
dc.contributor.authorEkeberg, Tomas-
dc.contributor.authorGraceffa, Rita-
dc.contributor.authorHeymann, Michael-
dc.contributor.authorHorke, Daniel A.-
dc.contributor.authorKnoška, Juraj-
dc.contributor.authorMariani, Valerio-
dc.contributor.authorNazari, Reza-
dc.contributor.authorOberthür, Dominik-
dc.contributor.authorSamanta, Amit K.-
dc.contributor.authorSierra, Raymond G.-
dc.contributor.authorStan, Claudiu A.-
dc.contributor.authorYefanov, Oleksandr-
dc.contributor.authorRompotis, Dimitrios-
dc.contributor.authorCorrea, Jonathan-
dc.contributor.authorErk, Benjamin-
dc.contributor.authorTreusch, Rolf-
dc.contributor.authorSchulz, Joachim-
dc.contributor.authorHogue, Brenda G.-
dc.contributor.authorGañán-Calvo, Alfonso M.-
dc.contributor.authorFromme, Petra-
dc.contributor.authorKüpper, Jochen-
dc.contributor.authorRode, Andrei V.-
dc.contributor.authorBajt, Saša-
dc.contributor.authorKirian, Richard A.-
dc.contributor.authorChapman, Henry N.-
dc.date.accessioned2019-04-24T11:05:35Z-
dc.date.available2019-04-24T11:05:35Z-
dc.date.issued2018-07-27-
dc.identifier.citationIUCrJ Pt 5 (5): 574-584-584 (2018-09-01)de_DE
dc.identifier.issn2052-2525de_DE
dc.identifier.urihttp://hdl.handle.net/11420/2394-
dc.description.abstractLiquid microjets are a common means of delivering protein crystals to the focus of X-ray free-electron lasers (FELs) for serial femtosecond crystallography measurements. The high X-ray intensity in the focus initiates an explosion of the microjet and sample. With the advent of X-ray FELs with megahertz rates, the typical velocities of these jets must be increased significantly in order to replenish the damaged material in time for the subsequent measurement with the next X-ray pulse. This work reports the results of a megahertz serial diffraction experiment at the FLASH FEL facility using 4.3 nm radiation. The operation of gas-dynamic nozzles that produce liquid microjets with velocities greater than 80 m s-1 was demonstrated. Furthermore, this article provides optical images of X-ray-induced explosions together with Bragg diffraction from protein microcrystals exposed to trains of X-ray pulses repeating at rates of up to 4.5 MHz. The results indicate the feasibility for megahertz serial crystallography measurements with hard X-rays and give guidance for the design of such experiments.en
dc.language.isoende_DE
dc.relation.ispartofIUCrJde_DE
dc.rightsinfo:eu-repo/semantics/openAccess-
dc.subjectFELsde_DE
dc.subjectX-ray FEL pulse trainsde_DE
dc.subjectX-ray free-electron lasersde_DE
dc.subjectmegahertz repetition ratesde_DE
dc.subject.ddc600: Technikde_DE
dc.titleRapid sample delivery for megahertz serial crystallography at X-ray FELsde_DE
dc.typeArticlede_DE
dc.identifier.urnurn:nbn:de:gbv:830-882.031652-
dc.identifier.doi10.15480/882.2221-
dc.type.diniarticle-
dc.subject.ddccode600-
dcterms.DCMITypeText-
tuhh.identifier.urnurn:nbn:de:gbv:830-882.031652-
tuhh.oai.showtruede_DE
tuhh.abstract.englishLiquid microjets are a common means of delivering protein crystals to the focus of X-ray free-electron lasers (FELs) for serial femtosecond crystallography measurements. The high X-ray intensity in the focus initiates an explosion of the microjet and sample. With the advent of X-ray FELs with megahertz rates, the typical velocities of these jets must be increased significantly in order to replenish the damaged material in time for the subsequent measurement with the next X-ray pulse. This work reports the results of a megahertz serial diffraction experiment at the FLASH FEL facility using 4.3 nm radiation. The operation of gas-dynamic nozzles that produce liquid microjets with velocities greater than 80 m s-1 was demonstrated. Furthermore, this article provides optical images of X-ray-induced explosions together with Bragg diffraction from protein microcrystals exposed to trains of X-ray pulses repeating at rates of up to 4.5 MHz. The results indicate the feasibility for megahertz serial crystallography measurements with hard X-rays and give guidance for the design of such experiments.de_DE
tuhh.publisher.doi10.1107/S2052252518008369-
tuhh.publication.instituteBildverarbeitungssysteme E-2de_DE
tuhh.identifier.doi10.15480/882.2221-
tuhh.type.opus(wissenschaftlicher) Artikel-
tuhh.institute.germanBildverarbeitungssysteme E-2de
tuhh.institute.englishBildverarbeitungssysteme E-2de_DE
tuhh.gvk.hasppnfalse-
openaire.rightsinfo:eu-repo/semantics/openAccessde_DE
dc.type.driverarticle-
dc.rights.cchttps://creativecommons.org/licenses/by/2.0/de_DE
dc.type.casraiJournal Article-
tuhh.container.issuePt. 5de_DE
tuhh.container.volume5de_DE
tuhh.container.startpage574de_DE
tuhh.container.endpage584de_DE
dc.rights.nationallicensefalsede_DE
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item.creatorGNDAwel, Salah-
item.creatorGNDMorgan, Andrew J.-
item.creatorGNDAyyer, Kartik-
item.creatorGNDGevorkov, Yaroslav-
item.creatorGNDFleckenstein, Holger-
item.creatorGNDRoth, Nils-
item.creatorGNDAdriano, Luigi-
item.creatorGNDBean, Richard-
item.creatorGNDBeyerlein, Kenneth R.-
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item.creatorGNDCoe, Jesse-
item.creatorGNDCruz-Mazo, Francisco-
item.creatorGNDEkeberg, Tomas-
item.creatorGNDGraceffa, Rita-
item.creatorGNDHeymann, Michael-
item.creatorGNDHorke, Daniel A.-
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item.creatorGNDMariani, Valerio-
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item.creatorGNDOberthür, Dominik-
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item.creatorGNDTreusch, Rolf-
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crisitem.author.parentorgStudiendekanat Elektrotechnik, Informatik und Mathematik-
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