Publisher DOI: 10.1109/ISBI.2018.8363808
Title: Imaging and moving magnetic beads with magnetic particle imaging for targeted drug delivery
Language: English
Authors: Griese, Florian  
Ludewig, Peter 
Thieben, Florian  
Gdaniec, Nadine 
Knopp, Tobias 
Issue Date: 23-May-2018
Source: Proceedings - International Symposium on Biomedical Imaging : 1293-1296 (2018-05-23)
Journal or Series Name: Proceedings - International Symposium on Biomedical Imaging 
Abstract (english): Magnetic Particle Imaging has proven to resolve superparamagnetic nano-particles within 3D volumes with high sensitivity and with high temporal resolution. Lately, MPI was utilized to track, manipulate and navigate small ferromagnetic devices since the magnetic field topology for imaging is very suitable for generating magnetical forces. In this work, we demonstrate the ability to image and move micro-sized magnetic beads simultaneously with MPI. We are constantly switching between imaging and magnetic force mode to resolve the beads position and manipulate their movement. Beside imaging, the magnetic beads provide a flexible platform for carrying therapeutic substances which can be attached to the bead surface. In combination with force application and imaging this has the potential to provide a tool for automatic drug delivery, e.g. for specific tumor treatment and ischemic stroke dissolution.
ISBN: 978-153863636-7
ISSN: 1945-7928
Institute: Biomedizinische Bildgebung E-5 
Type: InProceedings (Aufsatz / Paper einer Konferenz etc.)
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