DC FieldValueLanguage
dc.contributor.authorGerlach, Stefan-
dc.contributor.authorKuhlemann, Ivo-
dc.contributor.authorErnst, Floris-
dc.contributor.authorFürweger, Christoph-
dc.contributor.authorSchlaefer, Alexander-
dc.date.accessioned2019-09-24T05:45:25Z-
dc.date.available2019-09-24T05:45:25Z-
dc.date.issued2017-09-26-
dc.identifier.citationBritish Journal of Radiology 1078 (90): 20160926 (2017-01-01)de_DE
dc.identifier.issn1748-880Xde_DE
dc.identifier.urihttp://hdl.handle.net/11420/3407-
dc.description.abstractObjective: Ultrasound provides good image quality, fast volumetric imaging and is established for abdominal image guidance. Robotic transducer placement may facilitate intrafractional motion compensation in radiation therapy. We consider integration with the CyberKnife and study whether the kinematic redundancy of a seven-degrees-of-freedom robot allows for acceptable plan quality for prostate treatments. Methods: Reference treatment plans were generated for 10 prostate cancer cases previously treated with the CyberKnife. Considering transducer and prostate motion by different safety margins, 10 different robot poses, and 3 different elbow configurations, we removed all beams colliding with robot or transducer. For each combination, plans were generated using the same strict dose constraints and the objective to maximize the target coverage. Additionally, plans for the union of all unblocked beams were generated. Results: In 9 cases the planning target coverage with the ultrasound robot was within 1.1 percentage points of the reference coverage. It was 1.7 percentage points for one large prostate. For one preferable robot position, kinematic redundancy decreased the average number of blocked beam directions from 23.1 to 14.5. Conclusion: The impact of beam blocking can largely be offset by treatment planning and using a kinematically redundant robot. Plan quality can be maintained by carefully choosing the ultrasound robot position and pose. For smaller planning target volumes the difference in coverage is negligible for safety margins of up to 35 mm. Advances in knowledge: Integrating a robot for online intrafractional image guidance based on ultrasound can be realized while maintaining acceptable plan quality for prostate cancer treatments with the CyberKnife.en
dc.description.sponsorshipFunded by Deutsche Forschungsgemeinschaft (grants ER 817/1–1 and SCHL 1844/3-1).de_DE
dc.language.isoende_DE
dc.publisherWileyde_DE
dc.relation.ispartofBJRde_DE
dc.subject.ddc600: Technikde_DE
dc.subject.ddc610: Medizinde_DE
dc.titleImpact of robotic ultrasound image guidance on plan quality in SBRT of the prostatede_DE
dc.typeArticlede_DE
dc.type.diniarticle-
dc.subject.ddccode610-
dc.subject.ddccode600-
dcterms.DCMITypeText-
tuhh.abstract.englishObjective: Ultrasound provides good image quality, fast volumetric imaging and is established for abdominal image guidance. Robotic transducer placement may facilitate intrafractional motion compensation in radiation therapy. We consider integration with the CyberKnife and study whether the kinematic redundancy of a seven-degrees-of-freedom robot allows for acceptable plan quality for prostate treatments. Methods: Reference treatment plans were generated for 10 prostate cancer cases previously treated with the CyberKnife. Considering transducer and prostate motion by different safety margins, 10 different robot poses, and 3 different elbow configurations, we removed all beams colliding with robot or transducer. For each combination, plans were generated using the same strict dose constraints and the objective to maximize the target coverage. Additionally, plans for the union of all unblocked beams were generated. Results: In 9 cases the planning target coverage with the ultrasound robot was within 1.1 percentage points of the reference coverage. It was 1.7 percentage points for one large prostate. For one preferable robot position, kinematic redundancy decreased the average number of blocked beam directions from 23.1 to 14.5. Conclusion: The impact of beam blocking can largely be offset by treatment planning and using a kinematically redundant robot. Plan quality can be maintained by carefully choosing the ultrasound robot position and pose. For smaller planning target volumes the difference in coverage is negligible for safety margins of up to 35 mm. Advances in knowledge: Integrating a robot for online intrafractional image guidance based on ultrasound can be realized while maintaining acceptable plan quality for prostate cancer treatments with the CyberKnife.de_DE
tuhh.publisher.doi10.1259/bjr.20160926-
tuhh.publication.instituteMedizintechnische Systeme E-1de_DE
tuhh.type.opus(wissenschaftlicher) Artikel-
tuhh.institute.germanMedizintechnische Systeme E-1de
tuhh.institute.englishMedizintechnische Systeme E-1de_DE
tuhh.gvk.hasppnfalse-
dc.type.driverarticle-
dc.type.casraiJournal Article-
tuhh.container.issue1078de_DE
tuhh.container.volume90de_DE
tuhh.container.articlenumber20160926de_DE
item.grantfulltextnone-
item.creatorGNDGerlach, Stefan-
item.creatorGNDKuhlemann, Ivo-
item.creatorGNDErnst, Floris-
item.creatorGNDFürweger, Christoph-
item.creatorGNDSchlaefer, Alexander-
item.openairecristypehttp://purl.org/coar/resource_type/c_6501-
item.fulltextNo Fulltext-
item.openairetypeArticle-
item.creatorOrcidGerlach, Stefan-
item.creatorOrcidKuhlemann, Ivo-
item.creatorOrcidErnst, Floris-
item.creatorOrcidFürweger, Christoph-
item.creatorOrcidSchlaefer, Alexander-
item.languageiso639-1en-
item.cerifentitytypePublications-
crisitem.author.deptMedizintechnische Systeme E-1-
crisitem.author.deptMedizintechnische Systeme E-1-
crisitem.author.parentorgStudiendekanat Elektrotechnik, Informatik und Mathematik-
crisitem.author.parentorgStudiendekanat Elektrotechnik, Informatik und Mathematik-
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