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Charakterisierung und numerische Simulation an Hautmodellen in einem Multi-Organ-Chip
Citation Link: https://doi.org/10.15480/882.2464
Publikationstyp
Doctoral Thesis
Date Issued
2019
Sprache
German
Author(s)
Advisor
Pörtner, Ralf
Referee
Title Granting Institution
Technische Universität Hamburg
Place of Title Granting Institution
Hamburg
Examination Date
2019-08-29
Institut
TORE-DOI
TORE-URI
Citation
Technische Universität Hamburg (2019)
Animal experiment for substance testing are controversially discussed. In the field of cosmetic they are already banned in Europe. For this reason, the demand for alternative methods is increasing. An interesting approach for this is the substance testing in an "organ-on-a-chip" system. For this purpose, a method for the determination of substance permeation of skin models in a small 96 well membrane insert system was developed, characterized and investigated. Furthermore, a simulation for the method was developed, analyzed and validated. The simulation is a good addition to the measurement and reduces the experimental effort.
DDC Class
570: Biowissenschaften, Biologie
610: Medizin
620: Ingenieurwissenschaften
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Dissertation Veröffentlichung-Hsu.pdf
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5.89 MB
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