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Electrical Impedance Spectroscopy for Characterization of Prostate PC-3 and du 145 Cancer Cells
Publikationstyp
Conference Paper
Date Issued
2019-07
Sprache
English
Institut
TORE-URI
Start Page
6485
End Page
6489
Article Number
8856627
Citation
Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS: 8856627 (2019-07)
Contribution to Conference
Publisher DOI
Scopus ID
The impedance profile of the human PC-3 and DU 145 prostate cancer cells were recorded and compared using Electrical Impedance Spectroscopy. Cells were measured in a special chamber using a four terminal setup to avoid parasitic effects of electrode polarization in low frequencies. Our results show that the two cancer cell lines are readily distinguishable by their impedance spectrum. As PC-3 cells have been shown to be spontaneously metastatic in previous xenograft experiments while DU 145 cells were non-metastatic, Electrical Impedance Spectroscopy has the potential to be developed into a simple diagnostic tool to distinguish metastatic from non-metastatic cells.