Schirmer, CedricCedricSchirmerBlaschczok, KatharinaKatharinaBlaschczokHusemann, UteUteHusemannLeupold, MarcoMarcoLeupoldZahnow, ChristianChristianZahnowRupprecht, JensJensRupprechtGlöckler, RainerRainerGlöcklerGreller, GerhardGerhardGrellerPörtner, RalfRalfPörtnerEibl, RegineRegineEiblEibl, DieterDieterEibl2019-10-282019-10-282017-10-20Chemie-Ingenieur-Technik 12 (89): 1766-1772 (2017-12-01)http://hdl.handle.net/11420/3659An in 2016 published DECHEMA guideline concerning process engineering characterization and a new Escherichia coli model process were utilized for the qualification of two geometrically similar stirred stainless steel bioreactors (30 L and 100 L working volume). The achieved results demonstrate that performing an additional biological model process is a valuable complement to the process engineering characterization. Optical densities of 27 (100 L) and 39 (30 L) were reached in the batch cultivation process.en1522-2640Chemie - Ingenieur - Technik20171217661772Wiley-VCH Verl.Escherichia coliMixing timeProcess engineering characterizationSpecific power inputStirred bioreactorVolumetric mass transfer coefficientTechnikIngenieurwissenschaftenStandardized qualification of stirred bioreactors for microbial biopharmaceutical production processesJournal Article10.1002/cite.201700039Other