Ritter, EricEricRitterSmirnova, IrinaIrinaSmirnova2019-04-252019-04-252018-03Chemie-Ingenieur-Technik 3 (90): 348-357 (2018-03)http://hdl.handle.net/11420/2415To evaluate the possibility of performing extractive biocatalysis in continuous mode, the hydrolysis of penicillin G in a micellar solution containing the nonionic surfactant Tergitol NP-7 was chosen as model system. While the product phenylacetic acid distributes into the micellar phase, 6-aminopenicillanic acid moves preferably into the aqueous phase. The yield in the continuous multi-step process was higher in comparison to equivalent batch systems. Overall, the results demonstrate the suitability of aqueous surfactant two-phase systems for continuous biocatalytic reactive extraction processes.en0009-286X20183348357Journal Article10.1002/cite.201700054Other