Gladiß, Anselm vonAnselm vonGladißGräser, MatthiasMatthiasGräserCordes, AileenAileenCordesBakenecker, Anna C.Anna C.BakeneckerBehrends, AndréAndréBehrendsChen, XinXinChenBuzug, Thorsten M.Thorsten M.Buzug2020-06-022020-06-022020-03-30International Journal on Magnetic Particle Imaging 1 (6): 2003004 (2020)http://hdl.handle.net/11420/6207Hybrid phantoms allow for measurement-based evaluation of particle samples, reconstruction algorithms and field sequences without need of a Magnetic Particle Imaging (MPI) scanning device. Even dynamic hybrid phantoms can be generated using dynamic magnetic offset fields. Multi-dimensional Magnetic Particle Spectrometers are capable of emulating both hybrid system matrices and hybrid phantoms, which can be reconstructed into images. It is shown that a spatial resolution of few hundred micrometres can be achieved for both one-and multi-dimensional excitation using MPI technology. The spatial resolution of reconstructed images increases when including additional receive channels into the reconstruction process. For multi-dimensional imaging the sine-based Lissajous trajectory outperforms the cosine-based Lissajous trajectory in terms of spatial resolution. Both the high signal to noise ratio of a spectrometer and the versatility of hybrid phantom design will enforce innovative measurement-based research on key parameters for MPI.en2365-903320201Infinite Science Publishinghttps://creativecommons.org/licenses/by/4.0/InformatikTechnikMedizinJournal Article10.15480/882.278810.18416/ijmpi.2020.200300410.15480/882.2788Journal Article