Huang, LeiLeiHuangSayoga, GiovanniGiovanniSayogaHollmann, FrankFrankHollmannKara, SelinSelinKara2019-08-052019-08-052018-08-07ACS Catalysis 9 (8): 8680-8684 (2018-09-07)http://hdl.handle.net/11420/3054A direct synthesis of lactams (5-, 6-, and 7-membered) starting from amino-alcohols in a bienzymatic cascade is reported. Horse liver alcohol dehydrogenase together with the NADH oxidase from Streptococcus mutans were applied for the oxidative lactamization of various amino alcohols. Crucial parameters for the efficiency of this cascade reaction were elucidated. This report represents a direct approach for biocatalytic oxidative lactamization reaction.en2155-5435ACS catalysis2018986808684ACSChemieTechnikHorse liver alcohol dehydrogenase-datalyzed oxidative lactamization of amino alcoholsJournal Article10.1021/acscatal.8b02355Journal Article