Schmiech, JonteJonteSchmiechWegner, MarieMarieWegnerWortmann, NadineNadineWortmannSobirey, EveEveSobireyDe Sousa Guerreiro, Helena I.Helena I.De Sousa GuerreiroKyselyova, AnnaAnnaKyselyovaRamdani, NoraNoraRamdaniKrause, DieterDieterKrause2024-12-192024-12-192024-11-21Journal of engineering and science in medical diagnostics and therapy 8 (3): JESMDT-24-1026 (2024-11-21)https://hdl.handle.net/11420/52637This work introduces version 2.0 of the Hamburg ANatomical NEurointerventional Simulator (HANNES): a novel modular neurointerventional simulator designed to provide a realistic platform for simulating various neurovascular pathologies and their endovascular therapies. Collaboratively developed by physicians and engineers, the neurointerventional simulator is designed with a modular product architecture combining standardized and variant modules to represent different training scenarios. The additively manufactured patient-based and patient-specific blood vessel tree consists of up to 13 individual components, including standardized features and interfaces for ease of connection. Patient-specific vessel models derived from medical imaging data allow customization and complexity adjustment. HANNES supports diverse neurointerventional training scenarios, including various modalities of aneurysm embolization, internal carotid artery (ICA)-stenosis, and thrombotic vessel occlusions, which can be treated through a transradial or transfemoral approach. The use and benefits of the model were evaluated with a group of trainees, who provided positive feedback, confirming the model's practicality and effectiveness in enhancing neurointerventional technical skills. In conclusion, HANNES represents a significant advancement in neurointerventional training, addressing the limitations of traditional training methods by simulating diverse disease patterns, enhancing medical staff's skills, and facilitating product testing.en2572-796620243ASME InternationalTechnology::610: Medicine, HealthTechnology::600: TechnologyJournal Article10.1115/1.4066935https://asmedigitalcollection.asme.org/medicaldiagnostics/article/8/3/031008/1207410/HANNES-A-Modular-Neurointerventional-TrainingJournal Article