Acevedo-Rocha, Carlos G.Carlos G.Acevedo-RochaHoesl, Michael G.Michael G.HoeslNehring, SebastianSebastianNehringRoyter, MarynaMarynaRoyterWolschner, ChristinaChristinaWolschnerWiltschi, BirgitBirgitWiltschiAntranikian, GarabedGarabedAntranikianBudisa, NediljkoNediljkoBudisa2019-09-052019-09-052013Catalysis Science and Technology 5 (3): 1198-1201 (2013)http://hdl.handle.net/11420/3294The incorporation of several non-canonical amino acids into the Thermoanaerobacter thermohydrosulfuricus lipase confers not only activity enhancement upon treatment with organic solvents (by up to 450%) and surfactants (resp. 1630%), but also protective effects against protein reducing (resp. 140%), alkylating (resp. 160%), and denaturing (resp.190%) agents as well as inhibitors (resp. 40%). This approach offers novel chemically diversified biocatalysts for hostile environments. © 2013 The Royal Society of Chemistry.en2044-47612013511981201RSC Publ.https://creativecommons.org/licenses/by-nc/3.0/NaturwissenschaftenChemieBiowissenschaften, BiologieTechnikIngenieurwissenschaftenJournal Article10.15480/882.1364610.1039/c3cy20712a10.15480/882.13646Journal Article