Morlock, MichaelMichaelMorlockKunze, JoachimJoachimKunzeWimmer, Markus A.Markus A.WimmerLohmann, Christoph H.Christoph H.Lohmann2024-03-122024-03-122012Seminars in Arthroplasty 23 (4): 283-285 (2012)https://hdl.handle.net/11420/46374Due to the wear-related problems with large diameter metal-on-metal THA components, ion levels of cobalt and chromium in blood or serum are used to identify bearings with high-wear rates. Threshold levels for critical concentrations for these two alloys are published and quite frequently revised. Patients and doctors are confused, if measured values are close to thresholds. A new approach is presented by an international expert panel endorsed by EFFORT and several national organizations suggesting the use of a range instead of a specific value as threshold. This approach supports the philosophy that metal ion concentrations by themselves are not a diagnosis but one - important - piece in the assessment of a patient with a metal-on-metal hip articulation.en1558-443720124283285ElsevierAdverse effectsIonsLarge headsMetal-on-metalResurfacingWearMedicine, HealthEngineeringJournal Article10.1053/j.sart.2012.12.002Journal Article