Prediger, AndreasAndreasPredigerBluma, ArneArneBlumaHöpfner, TimTimHöpfnerLindner, PatrickPatrickLindnerBeutel, SaschaSaschaBeutelMüller, Jakob J.Jakob J.MüllerHilterhaus, LutzLutzHilterhausLiese, AndreasAndreasLiese2023-10-262023-10-262011Chemical Engineering & Technology 34 (5): 837-840 (2011)https://hdl.handle.net/11420/43894In situ Microscopy (ISM) is an optical analysis method that allows non-invasive monitoring of processes in real-time. In this article online monitoring of enzyme carriers and the determination of their mechanical stability are presented as new application areas for ISM. As proof of principle the fragmentation of Lewatit VP OC 1600 particles in a stirred tank reactor is tracked. The image algorithm that was used to analyze the acquired image data is described and the results of the stability study are shown. Additional application possibilities of ISM in the area of two-phase systems are demonstrated. In situ microscopy (ISM) is an optical analysis method that allows noninvasive acquisition of image information from running processes. It is demonstrated how this analysis technique can be used to determine the mechanical stability of enzyme carriers. Furthermore, application possibilities of ISM for the characterization of two-phase systems are presented. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.en0930-751620115837840Wiley-VCHEnzyme catalysisImage processingIn situ microscopyProcess monitoringPhysicsLife Sciences, BiologyJournal Article10.1002/ceat.201000563Journal Article