Lee, YohanYohanLeeTittl, AndreasAndreasTittl2026-07-212026-07-212026-07-02Nature Photonics 20: 739–740 (2026)https://hdl.handle.net/11420/63992A new nanophotonic sensing strategy converts even subtle refractive-index changes into large intensity variations via radiative Q-factor modulation. Implemented in a bound-state-in-the-continuum (BIC) metasurface, the concept enables ultrasensitive and scalable biosensing of only a few tens of tumour extracellular vesicles within 15 minutes.en1749-48932026739740Nature ResearchNatural Sciences and Mathematics::530: PhysicsTechnology::617: Surgery, Regional Medicine, Dentistry, Ophthalmology, Otology, AudiologyCommentary10.1038/s41566-026-01942-y