Sabra, WaelWaelSabraBommareddy, Rajesh ReddyRajesh ReddyBommareddyMaheshwari, GarimaGarimaMaheshwariPapanikolaou, SeraphimSeraphimPapanikolaouZeng, An-PingAn-PingZeng2017-12-082017-12-082017-05-08Microbial cell factories 1 (16): 78- (2017-05-08)http://tubdok.tub.tuhh.de/handle/11420/1499Unlike the well-studied backer yeast where catabolite repression represents a burden for mixed substrate fermentation, Yarrowia lipolytica, an oleaginous yeast, is recognized for its potential to produce single cell oils and citric acid from different feedstocks. These versatilities of Y. lipolytica with regards to substrate utilization make it an attractive host for biorefinery application. However, to develop a commercial process for the production of citric acid by Y. lipolytica, it is necessary to better understand the primary metabolism and its regulation, especially for growth on mixed substrate.en1475-28592017178BioMed Centralhttps://creativecommons.org/licenses/by/4.0/Citric acidDual substrateGlyoxylate cycleOleaginous yeastPentose phosphate pathwayCitratesCitric AcidCulture MediaFermentationGene Expression ProfilingGlucoseGlycerolGlyoxylatesMetabolic Flux AnalysisOxygenPentose Phosphate PathwayYarrowiaChemieJournal Articleurn:nbn:de:gbv:830-8821791710.15480/882.149611420/149910.1186/s12934-017-0690-010.15480/882.1496Journal Article