Belushkin, A.A.BelushkinYesilkoy, F.F.YesilkoySoler, M.M.SolerTittl, AndreasAndreasTittlOzdemir, C.C.OzdemirXiaokang, L.L.XiaokangAltug, H.H.Altug2026-04-012026-04-01201620th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Microtas 2016https://hdl.handle.net/11420/62496This paper presents how the ultimate sensitivity of a surface-based plasmonic Au nanohole array (Au-NHA) biosensor can be enhanced by a proper microfluidic design, improving analyte delivery for protein-protein interactions and leading to 10 times better limit of detection (LOD). We demonstrate the correspondence of experimental in-situ results with theoretical and numerical estimations for different microfluidic channel designs.enBiosensorsMicrofluidicsMultiplexingPlasmonicsTechnology::620: EngineeringConference Paper