GAMS code for: Reactor network synthesis of enzymatic cascades using superstructure optimization

Chandra, SwastikSwastikChandraPaschalidis, LeandrosLeandrosPaschalidisKinau, Siv MagdalenaSiv MagdalenaKinauSkiborowski, MirkoMirkoSkiborowski2026-06-162026-06-162026-06-16https://hdl.handle.net/11420/63508This repository contains the GAMS optimization scripts and include files used to implement a nonlinear programming (NLP) framework for superstructure-based reactor network synthesis. The framework handles flexible network configurations combining Continuous Stirred-Tank Reactors (CSTR) and tubular Cross-Flow Reactors (CFR) without relying on binary or integer choices. The implementation includes scripts for framework validation via the classical Van de Vusse reaction network and application to a multi-enzyme cascade following the oxidative Weimberg pathway.enhttps://mit-license.org/Reactor Networknonlinear programmingGeneral Algebraic Modeling SystemEnzymatic CascadesReaction EngineeringSuperstructure OptimizationWeimberg PathwayVan de Vusse ReactionRadau CollocationTechnology::660: Chemistry; Chemical Engineering::660.2: Chemical EngineeringGAMS code for: Reactor network synthesis of enzymatic cascades using superstructure optimizationSoftwarehttps://doi.org/10.15480/882.1732110.15480/882.17321Skiborowski, MirkoMirkoSkiborowski10.69997/sct.121572