Löbler, MarianMarianLöblerRehmer, AnnelieAnnelieRehmerGuthoff, RudolfRudolfGuthoffMartin, HeinerHeinerMartinSternberg, KatrinKatrinSternbergStachs, OliverOliverStachs2024-03-262024-03-262011Veterinary Ophthalmology 14 (1): 66-68 (2011)https://hdl.handle.net/11420/46736Objective To utilize the Icare tonometer TAO1 for intraocular pressure (IOP) determination in experimental animals. To calculate true IOP calibration functions for rabbit and porcine eyes.Animals Enucleated eyes of 3-year-old healthy experimental rabbits (New Zealand white), and healthy 1 year old experimental pigs (Deutsche Landrasse) were used for the determination of IOP.Procedures Manometric (Geuder GmbH, Heidelberg/Germany) and rebound tonometry (Icare tonometer TAO1, Icare, Helsinki/Finland) were used to record IOP in enucleated animal eyes (rabbit n = 2, pig n = 3).Results The Icare tonometer TAO1 measurements underestimated true IOP by 37-60% in rabbit eyes and 17-63% in porcine eyes. IOP values obtained by both rebound and manometric tonometry for rabbit and porcine eyes followed a linear regression curve. Linear functions were calculated to correct the Icare tonometer TAO1 measurements to true IOP for both rabbit (p = 1.4244pic + 4.2421) and porcine eyes (p = 1.0799pic + 5.8557). Conclusions The Icare tonometer TAO1 can be utilized for IOP determination in rabbit and porcine eyes when measured values are corrected with the appropriate linear function. © 2011 American College of Veterinary Ophthalmologists.en1463-5216201116668Wiley-BlackwellGlaucomaIOPLinear functionPigRabbitRebound tonometryLife Sciences, BiologyJournal Article10.1111/j.1463-5224.2010.00794.xJournal Article