Dietz, DavidDavidDietzSabra, WaelWaelSabraZeng, An-PingAn-PingZeng2019-06-072019-06-072013-05-24AMB Express 1 (3): Art.-Nr. 29 (2013)http://hdl.handle.net/11420/2744In this work a defined co-culture of the lactic acid bacterium Lactobacillus zeae and the propionate producer Veillonella criceti has been studied in continuous stirred tank reactor (CSTR) and in a dialysis membrane reactor. It is the first time that this reactor type is used for a defined co-culture fermentation. This reactor allows high mixing rates and working with high cell densities, making it ideal for co-culture investigations. In CSTR experiments the co-culture showed over a broad concentration range an almost linear correlation in consumption and production rates to the supply with complex nutrients. In CSTR and dialysis cultures a strong growth stimulation of L. zeae by V. criceti was shown. In dialysis cultures very high propionate production rates (0.61 g L-1h-1) with final titers up to 28 g L-1 have been realized. This reactor allows an individual, intracellular investigation of the co-culture partners by omic-technologies to provide a better understanding of microbial communities. © 2013 Bel-Rhlid et al.en2191-085520131Art.-Nr. 29Springerhttps://creativecommons.org/licenses/by/2.0/Propionic AcidLactic AcidLactobacillus zeaeVeillonella cricetiDialysis chamber reactorCo-cultureFermentationBiowissenschaften, BiologieJournal Articleurn:nbn:de:gbv:830-882.03579510.15480/882.228010.1186/2191-0855-3-2910.15480/882.2280Other