This contribution outlines a multiscale simulation approach for analysis of a Wurster coating process occurring in a fluidized bed. The processes occurring in the apparatus are described on four different time and length scales: The Discrete Element Method coupled with Computational Fluid Dynamics, where each particle is considered as a separate entity and its motion in fluid field is calculated, play a central role in the modeling framework. On the macroscale, the Population Balance Model describes the particle growth. The nozzle zone model calculates the wetting and overspray rate on the mesoscale. The model on the lowest scale predicts the impact behavior of wetted particles. The influence of key processing parameters, such as gap distance or atomization air flow, on the particle-fluid dynamics during coating process is analyzed. In order to get material parameters, such as coefficient of restitution and friction, a set of experimental investigations of a model material is performed.