Prof. Dr.-Ing. Ralf Pörtner

Results 1-20 of 65

Issue DateTitleTypeAuthor(s)
1Jan-2023Fulltext availableOpen AccessComparison of mechanistic and hybrid modeling approaches for characterization of a CHO cultivation process: Requirements, pitfalls and solution pathsArticleBayer, Benjamin ; Duerkop, Mark ; Pörtner, Ralf  ; Möller, Johannes 
22023CHO and HepG2 Single-Cell Characterization With Planar Microchip Sensors up to 40 GHzArticleSavić, Aleksandar  ; Freiberger, Fabian ; Pörtner, Ralf  ; Jacob, Arne 
34-Nov-2022Fulltext availableOpen AccessGeneration and evaluation of input values for computational analysis of transport processes within tissue culturesReview (Article)Fattahi, Ehsan ; Taheri, Shahed ; Schilling, Arndt F. ; Becker, Thomas ; Pörtner, Ralf  
418-Aug-2022Fulltext availableOpen AccessSpecial issue “Bioprocess systems engineering applications in pharmaceutical manufacturing”EditorialPörtner, Ralf  ; Möller, Johannes 
51-Jun-2022A capacitive microwave sensor with guard electrode for single cell characterizationArticleSavić, Aleksandar  ; Freiberger, Fabian ; Pörtner, Ralf  ; Jacob, Arne 
62-Feb-2022Fulltext availableOpen AccessModel-assisted DoE applied to microalgae processesArticleGassenmeier, Veronika ; Deppe, Sahar ; Hernández Rodríguez, Tanja ; Kuhfuß, Fabian ; Moser, André ; Hass, Volker C. ; Kuchemüller, Kim Beatrice ; Pörtner, Ralf  ; Möller, Johannes ; Ifrim, George ; Frahm, Björn 
75-Jan-2022Fulltext availableOpen AccessNew insights from locally resolved hydrodynamics in stirred cell culture reactorsArticleFreiberger, Fabian ; Budde, Jens ; Ateş, Eda ; Schlüter, Michael ; Pörtner, Ralf  ; Möller, Johannes 
8Jun-2021Fulltext availableOpen AccessConsiderations of the impacts of cell-specific growth and production rate on clone selection : a simulation studyArticleHernández Rodríguez, Tanja ; Morerod, Sophie ; Pörtner, Ralf  ; Wurm, Florian M. ; Frahm, Björn 
92-Mar-2021Fulltext availableOpen AccessAn overview of drive systems and sealing types in stirred bioreactors used in biotechnological processesArticleSchirmer, Cedric ; Maschke, Rüdiger ; Pörtner, Ralf  ; Eibl, Dieter 
10Mar-2021Fulltext availableOpen AccessDigital twins for tissue culture techniques : concepts, expectations, and state of the artArticleMöller, Johannes ; Pörtner, Ralf  
11Mar-2021Fulltext availableOpen AccessRegulation of pyruvate dehydrogenase complex related to lactate switch in CHO cellsArticleMöller, Johannes ; Bhat, Krathika ; Guhl, Lotta ; Pörtner, Ralf  ; Jandt, Uwe ; Zeng, An-Ping  
1220-Jan-2021Fulltext availableOpen AccessModel-assisted DoE software: optimization of growth and biocatalysis in Saccharomyces cerevisiae bioprocessesArticleMoser, André ; Kuchemüller, Kim Beatrice ; Deppe, Sahar ; Hernández Rodríguez, Tanja ; Frahm, Björn ; Pörtner, Ralf  ; Hass, Volker C. ; Möller, Johannes 
1313-Jan-2021Fulltext availableOpen AccessModel-based workflow for scale-up of process strategies developed in miniaturized bioreactor systemsArticleArndt, Lukas ; Wiegmann, Vincent ; Kuchemüller, Kim Beatrice ; Baganz, Frank ; Pörtner, Ralf  ; Möller, Johannes 
142021Digital Twins and Their Role in Model-Assisted Design of ExperimentsChapter (Book)Kuchemüller, Kim Beatrice ; Pörtner, Ralf  ; Möller, Johannes 
1529-Dec-2020Fulltext availableDynamic parameter estimation and prediction over consecutive scales, based on moving horizon estimation: applied to an industrial cell culture seed trainArticleHernández Rodríguez, Tanja ; Posch, Christoph ; Pörtner, Ralf  ; Frahm, Björn 
1619-Oct-2020Fulltext availableOpen AccessNMPC-based workflow for simultaneous process and model development applied to a fed-batch process for recombinant C. glutamicumArticleLevermann, Philipp ; Freiberger, Fabian ; Katha, Uma ; Zaun, Henning ; Möller, Johannes ; Hass, Volker C. ; Schoop, Karl Michael ; Kuballa, Jürgen ; Pörtner, Ralf  
174-Mar-2020Fulltext availableOpen AccessQuantification of the dynamics of population heterogeneities in CHO cultures with stably integrated fluorescent markersArticleMöller, Johannes ; Rosenberg, Marcel ; Riecken, Kristoffer ; Pörtner, Ralf  ; Zeng, An-Ping  ; Jandt, Uwe 
184-Mar-2020Fulltext availableOpen AccessModel uncertainty-based evaluation of process strategies during scale-up of biopharmaceutical processesArticleMöller, Johannes ; Hernández Rodríguez, Tanja ; Müller, Jan ; Arndt, Lukas ; Kuchemüller, Kim Beatrice ; Frahm, Björn ; Eibl, Regine ; Eibl, Dieter ; Pörtner, Ralf  
192020Towards integration of prior knowledge and propagation of uncertainty for digital twins of biopharmaceutical production processesPosterHernández Rodríguez, Tanja ; Posch, Christoph ; Pörtner, Ralf  ; Frahm, Björn 
202020Estimation of process model parametersChapter (Book)Deppe, Sahar ; Frahm, Björn ; Hass, Volker C. ; Hernández Rodríguez, Tanja ; Kuchemüller, Kim Beatrice ; Möller, Johannes ; Pörtner, Ralf