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  4. Synthesis, characterization and antibacterial assessment of sio2-hydroxypropylmethyl cellulose hybrid materials with embedded silver nanoparticles
 
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Synthesis, characterization and antibacterial assessment of sio2-hydroxypropylmethyl cellulose hybrid materials with embedded silver nanoparticles

Publikationstyp
Journal Article
Date Issued
2014-09-23
Sprache
English
Author(s)
Angelova, Tsvetelina  
Rangelova, Nadezhda  
Dineva, Hristina  
Georgieva, Nelly  
Müller, Rudolf  
Institut
Technische Biokatalyse V-6  
TORE-URI
http://hdl.handle.net/11420/9910
Journal
Biotechnology & biotechnological equipment  
Volume
28
Issue
4
Start Page
747
End Page
752
Citation
Biotechnology and Biotechnological Equipment 28 (4): 747-752 (2014)
Publisher DOI
10.1080/13102818.2014.944789
Scopus ID
2-s2.0-84910025848
Publisher
Taylor and Francis
Antibacterial SiO2 hybrid materials based on tetraethyl orthosilicate (TEOS), hydroxypropylmethylcellulose (HPMC) and silver were prepared by the sol-gel method. The content of cellulose derivate was 5 wt% and the silver concentration varied from 0.5 wt% to 2.5 wt%. The amorphous nature, morphology and antibacterial behaviour were studied. Fourier transform infrared (FTIR) spectra of the hybrids showed characteristic peaks for SiO2 network. Scanning electron microscope (SEM) analysis confirmed the formation of spherically shaped silver nanoparticles with a size of 30 nm on the matrix surfaces. Bacillus subtilis and Escherichia coli K12 were used as model microorganisms. The hybrid materials demonstrated bacteriostatic and bactericidal effect on the tested bacteria. Highest sensitivity to the obtained hybrids was observed in B. subtilis with significant lag-phase delay and biggest inhibition zone sizes.
Subjects
Antibacterial activity
Hydroxypropylmethyl cellulose
Silver nanoparticles
SiO 2
DDC Class
570: Biowissenschaften, Biologie
Funding Organisations
European Social Fund
Bulgarian Ministry of Education and Science
More Funding Information
This work was supported by the European Social Fund, Operational Programme Human Resources Development (2007-2013) and the Bulgarian Ministry of Education and Science [grant number BG051PO001-3.3.06-0059].
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