Enzymatic carboxylation of resorcinol in aqueous triethanolamine: first steps towards a lab-scale production process
Title Granting Institution
Technische Universität Hamburg
Place of Title Granting Institution
Technische Universität Hamburg (2022)
The triethanolamine-mediated enzymatic carboxylation of resorcinol was investigated, where CO2 is used as resource. The reaction system was characterized and different strategies to improve reaction yields tested. In this work, a process was established and characterized to produce 2,6-dihydroxybenzoic acid in a purity of over 99.8%. This was enabled by the application of a suitable adsorbent for in situ product removal. Furthermore, the CO2 gassing was optimized with microbubble gassing, which improved the mass transfer, CO2 utilization and reduced foam formation. The gained insights into the amine-based enzymatic carboxylation helps to promote this process for industrial application.
660: Technische Chemie
Ohde_Daniel_Dissertation_Enzymatic Carboxylation of Resorcinol in Aqueous Triethanolamine.pdf