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Iron(II)-catalyzed biomimetic aerobic oxidation of alcohols
Citation Link: https://doi.org/10.15480/882.2725
Publikationstyp
Journal Article
Date Issued
2020-01-24
Sprache
English
Institut
TORE-DOI
TORE-URI
Volume
59
Issue
13
Start Page
5403
End Page
5406
Citation
Angewandte Chemie - International Edition 13 (59): 5403-5406 (2020)
Publisher DOI
Scopus ID
Publisher
Wiley-VCH
We report the first FeII-catalyzed biomimetic aerobic oxidation of alcohols. The principle of this oxidation, which involves several electron-transfer steps, is reminiscent of biological oxidation in the respiratory chain. The electron transfer from the alcohol to molecular oxygen occurs with the aid of three coupled catalytic redox systems, leading to a low-energy pathway. An iron transfer-hydrogenation complex was utilized as a substrate-selective dehydrogenation catalyst, along with an electron-rich quinone and an oxygen-activating Co(salen)-type complex as electron-transfer mediators. Various primary and secondary alcohols were oxidized in air to the corresponding aldehydes or ketones with this method in good to excellent yields.
Subjects
aerobic oxidation
biomimetic reactions
electron transfer
homogeneous catalysis
iron
DDC Class
540: Chemie
600: Technik
More Funding Information
Financial support from the Swedish Research Council (2016-03897), the Olle Engkvist Foundation, and the Knut and Alice Wallenberg Foundation (KAW 2016.0072).
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