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Prozessentwicklung zur biotechnologischen Produktion von Acrolein aus Nebenprodukten der Bioethanolherstellung
Citation Link: https://doi.org/10.15480/882.1162
Other Titles
Process development for the biotechnological production of acrolein from bioethanol production by-products
Publikationstyp
Doctoral Thesis
Date Issued
2013
Sprache
German
Author(s)
Advisor
Title Granting Institution
Technische Universität Hamburg
Place of Title Granting Institution
Hamburg
Examination Date
2013-12-19
Institut
TORE-DOI
Since fossile rescources are of limited availability, chemicals from renewable resources become more interesting for scientists and the industry. Promising platform chemicals include 3-hydroxypropionaldehyde and its anhydride acrolein. However, existing approaches are not sufficient for an economic production in industrial scale. Therefore, it was examined in this thesis how far stillage, a glycerol containing byproduct of the bioethanol production process, can be used for the 3-hydroxypropionaldehyde/ acrolein production and how far this production can be integrated into the bioethanol process according to the biorefinery concept to solve existing problems and to reduce production costs. Calculations as well as batchwise and continuous experiments were carried out in 5 ml to 2 l scale in the area of biocatalyst production, biotransformation, purification and cost estimation. The whole cell biocatalyst Lactobacillus reuteri ATCC 53608 is not able to use the yeast cells from bioethanol production residues for its growth. However, it has been shown that it does not need all the nutrients in MRS medium and yeast extract is sufficient as the only source of amino acids and vitamins for its growth and enzyme production. The 3-HPA production in bioethanol production residues is 68 % higher than in a comparable aqueous glycerol solution under the same conditions and it requires less biocatalyst. A combination of dehydration and simple distillation is suitable to convert 3-hydroxypropionaldehyde into acrolein and separate it from the biotransformation broth at 37 ° C. 105 ± 8 g/l acrolein in aqueous solution were obtained in high purity. The cost estimation of a possible process has shown that the calculated cost for acrolein can likely catch up with production costs from crude oil in the near future with appropriate optimization. Hence it was shown that basing the process on stillage from the bioethanol process can improve the biotechnological production of 3-hydroxypropionaldehyde/ acrolein from renewable resources.
Subjects
3-Hydroxypropionaldehyd
Plattformchemikalie
Biotransformation
Bioraffinerie
Bioethanol
3-Hydroxypropionaldehyde
platform chemical
biotransformation
biorefinery
bioethanol
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Dissertation_Oehmke.pdf
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