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A tunable scaffold of microtubular graphite for 3D cell growth
Citation Link: https://doi.org/10.15480/882.1989
Publikationstyp
Journal Article
Date Issued
2016-06-03
Sprache
English
TORE-DOI
Volume
8
Issue
24
Start Page
14980
End Page
14985
Citation
ACS Applied Materials and Interfaces 24 (8): 14980-14985 (2016-06-22)
Publisher DOI
Scopus ID
Publisher
Soc.
Aerographite (AG) is a novel carbon-based material that exists as a self-supportive 3D network of interconnected hollow microtubules. It can be synthesized in a variety of architectures tailored by the growth conditions. This flexibility in creating structures presents interesting bioengineering possibilities such as the generation of an artificial extracellular matrix. Here we have explored the feasibility and potential of AG as a scaffold for 3D cell growth employing cyclic RGD (cRGD) peptides coupled to poly(ethylene glycol) (PEG) conjugated phospholipids for surface functionalization to promote specific adhesion of fibroblast cells. Successful growth and invasion of the bulk material was followed over a period of 4 days.
Subjects
aerographite
tissue engineering
3D scaffold
cyclic RGD
fibroblasts
DDC Class
600: Technik
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acsami.6b00778.pdf
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