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Process and cultivation strategies for the human industrial cell line AGE1.HN
Citation Link: https://doi.org/10.15480/882.1203
Other Titles
Prozessführungs- und Kultivierungsstrategien für die humane Produktionszelllinie AGE1.HN
Publikationstyp
Doctoral Thesis
Date Issued
2014
Sprache
English
Author(s)
Advisor
Pörtner, Ralf
Title Granting Institution
Technische Universität Hamburg
Place of Title Granting Institution
Hamburg
Examination Date
2014-01-10
Institut
TORE-DOI
This work focuses on the development of process and cultivation strategies for a systematic characterization and optimization of mammalian cell cultures, especially for the novel human industrial cell line AGE1.HN. This cell line was studied within the collaborative project SysLogics -Systems Biology of Cell Culture for Biologics- with the final goal of generating quantitative data on mammalian cell metabolism. The strategies developed in this work establish a solid basis for systematic studies with mammalian production cell lines, by allowing for their characterization from an engineering point of view, and the implementation of results in systems biology research.
Subjects
Zellkultur
Prozessstandardisierung
Synchronisation
Elutriation
Fed-Batch
cell culture
process standardization
synchronization
elutriation
fed-batch
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20141116_Platas_Dissertation_ohne_Lebenslauf.pdf
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3.73 MB
Format
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