Efficient hybrid 3D system calibration for magnetic particle imaging systems using a dedicated device

Image reconstruction in magnetic particle imaging is often performed using a system matrix based approach. The acquisition of a system matrix is a time-consuming calibration which may take several weeks and thus, is not feasible for a clinical device. Due to hardware characteristics of the receive chain, a system matrix may not even be used in similar devices but has to be acquired for each imager. In this work, a dedicated device is used for measuring a hybrid system matrix. It is shown that the measurement time of a 3D system matrix is reduced by 96%. The transfer function of the receive chains is measured, which allows the use of the same system matrix in multiple devices. Equivalent image reconstruction results are reached using the hybrid system matrix. Furthermore, the inhomogeneous sensitivity profile of receive coils is successfully applied to a hybrid system matrix. It is shown that each aspect of signal acquisition in magnetic particle imaging can be taken into account using hybrid system matrices. It is favourable to use a hybrid system matrix for image reconstruction in terms of measurement time, signal-to-noise ratio and discretisation.

DDC Class

004: Informatik

610: Medizin

More Funding Information

Federal ministry of education and research (BMBF, Grant Nos. 13W0069A and 13GW0230B). Open Access funding enabled and organized by Projekt DEAL.

Publication version

submittedVersion

Lizenz

https://creativecommons.org/licenses/by/4.0/

Name

s41598-020-75122-5.pdf

Size

1.92 MB

Format

Adobe PDF

Options

Efficient hybrid 3D system calibration for magnetic particle imaging systems using a dedicated device