A general process design methodology for membrane-assisted hybrid processes-deterministic mixed-integer process optimization
Hybrid processes are characterized by the combination of unit operations with different physical separation principles and have the ability to overcome limitations of the single unit operations. The combination of a membrane process with a distillation process allows crossing of distillation boundaries, since membrane processes are not limited to vapour-liquid-equilibrium. At the same time, unlike purely membrane based processes, the hybrid process also allows for sharp separations. To introduce a general process design methodology for membrane-assisted hybrid processes a recently reported process synthesis framework is extended with the required models for the membrane process. This paper presents a systematic procedure for the deterministic mixed-integer optimization of membrane-assisted hybrid separation processes.