Supercritical fluid simulated moving bed chromatography for the separation of ethyl linoleate and ethyl oleate

Journal
The journal of supercritical fluids  
Volume
66
Start Page
129
End Page
136
Citation
Journal of Supercritical Fluids (66): 129-136 (2012)
Publisher DOI
10.1016/j.supflu.2012.02.015
Scopus ID
2-s2.0-84860670235
Publisher
Elsevier Science
Supercritical fluid-simulated moving bed (SF-SMB) chromatography is an attractive technology thanks to the outstanding performance of continuous countercurrent adsorption processes in combination with the tunability of eluent strength of supercritical CO 2. This work focuses on the process development steps of simulated moving bed chromatography for the separation of ethyl linoleate and ethyl oleate on silica gel using supercritical carbon dioxide under linear conditions. Adsorption isotherms of the components of interest were determined at analytical scale and applied together with the equilibrium theory for the design of a two-step SF-SMB process for the separation of the fatty acid ethyl esters. Results of the experimental validation of the continuous chromatographic separation of ethyl linoleate and ethyl oleate are shown and discussed in detail.
Subjects
Fatty acid ethyl esters
Linear adsorption coefficient
Simulated moving bed chromatography (SMB)
Supercritical fluid chromatography (SFC)
DDC Class
530: Physik