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Dissolving carbon dioxide in high viscous substrates to accelerate biocatalytic reactions
Publikationstyp
Journal Article
Publikationsdatum
2011-06-08
Sprache
English
Enthalten in
Volume
108
Issue
11
Start Page
2765
End Page
2769
Citation
Biotechnology and Bioengineering 108 (11): 2765-2769 (2011)
Publisher DOI
Scopus ID
PubMed ID
21656709
Publisher
Wiley
Solvent free biotransformation of polyglycerol-3 and lauric acid yields polyglycerol-3-laurate and water. This conversion can be catalyzed by Novozym 435. However, the performance is limited by the viscosity of polyglycerol as well as of polyglycerol-3-laurate. A decrease of viscosity by increasing reaction temperature is only possible in a certain temperature range because of the limited stability of the applied enzyme. By dissolving high dense carbon dioxide into the reaction system the viscosity could be reduced, keeping the temperature at an acceptable level at the same time. Thus the reaction rate was increased by a factor of 4 while working at a pressure of 280 bar and 60°C. © 2011 Wiley Periodicals, Inc.
Schlagworte
Esterification
High dense carbon dioxide
Lipase
Personal care product
Solvent free
Viscosity
DDC Class
570: Biowissenschaften, Biologie