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Influence of the specimen scan condition on the finite element voxel model of human vertebral cancellous bone
Publikationstyp
Journal Article
Date Issued
2015-07-03
Sprache
English
Author(s)
Institut
TORE-URI
Volume
3
Issue
3
Start Page
172
End Page
176
Citation
Computer Methods in Biomechanics and Biomedical Engineering: Imaging and Visualization 3 (3): 172-176 (2015-07-03)
Publisher DOI
Scopus ID
Quantitative computed tomography-based finite element (FE) modelling technique is a promising tool for the prediction of bone fracture risk in clinic. However, FE models created from CT image datasets acquired at different scan conditions may yield comparably different results. The aim of this study was to investigate the influence of specimen scan condition on the FE models. Eight thoracolumbar vertebrae (T12) were scanned prior to autopsy (in situ). Afterwards, the segments (T10–L1) were dissected and scanned again under in vitro condition. Both scans were performed with high-resolution scan protocols, and the images were reconstructed with a voxel size of 0.18 mm × 0.18 mm × 0.3 mm. FE models with the cuboid volume of interest from the vertebral cancellous part were created. Inhomogeneous nonlinear bone properties were defined and the axial compression was simulated. The apparent bone mineral density, the modulus and yield strength showed significant differences in the two scan condition groups. In conclusion, the specimen scan condition may have to be considered when transferring the in vitro research knowledge into in vivo clinical applications.
Subjects
finite element model
in situ
in vitro
QCT image
scan condition
vertebra