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Untersuchung von selbstklebenden topischen Matrix-Systemen zur Wirkstofffreisetzung aus kosmetischen und dermatologischen Patches
Citation Link: https://doi.org/10.15480/882.1174
Other Titles
Investigation of topical adhesive matrix systems for drug release from cosmetic and dermatologic patches
Publikationstyp
Doctoral Thesis
Date Issued
2014
Sprache
German
Author(s)
Advisor
Title Granting Institution
Technische Universität Hamburg
Place of Title Granting Institution
Hamburg
Examination Date
2014-05-20
Institut
TORE-DOI
The selection of a suitable pressure sensitive adhesive represents an important step in the design of a transdermal drug delivery system (TDDS). In this study the percutaneous absorption of drugs during the application of adhesive TDDSs was investigated. Diffusion processes within the adhesive of a TDDS could be observed with a newly developed method based on confocal Raman microscopy. With the knowledge gained in these studies a new concept for the development of a TDDS was established. Finally this concept was tested successfully with two different drugs.
Subjects
skin
permeation
drug release
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