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Non-stationary 13C metabolic flux analysis of Chinese hamster ovary cells in batch culture using extracellular labeling highlights metabolic reversibility and compartmentation
Citation Link: https://doi.org/10.15480/882.2177
Publikationstyp
Journal Article
Date Issued
2014-04-28
Sprache
English
Institut
TORE-DOI
TORE-URI
Journal
Citation
BMC systems biology 1 (8): 50 (2014-04-28)
Publisher DOI
Scopus ID
Publisher
BioMed Central
Mapping the intracellular fluxes for established mammalian cell lines becomes increasingly important for scientific and economic reasons. However, this is being hampered by the high complexity of metabolic networks, particularly concerning compartmentation.
Subjects
Chinese hamster ovary cells
Metabolic Flux Analysis
Mitochondria
Compartmentation
Mammalian metabolism
CHO
Mammalian cell culture
Metabolic transport
Reversibility
DDC Class
620: Ingenieurwissenschaften
More Funding Information
Institute of Cell Culture Technology (University Bielefeld, Germany) ; the BMBF (German Federal Ministry of Education and Research)
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1752-0509-8-50.pdf
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1.7 MB
Format
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