Influence of the system matrix on channel leakage artifacts in multi-contrast MPI

Magnetic Particle Imaging (MPI) is a tracer-based medical imaging modality with great potential due to its high sensitivity, high spatiotemporal resolution, and ability to quantify the tracer concentration. Image reconstruction in MPI is an ill-posed problem, which can be addressed by the use of regularization methods. Single-and multi-contrast MPI reconstructions produce different kinds of artifacts. In this work, the multi-contrast MPI channel leakage is introduced and an analysis of the multi-contrast MPI system matrix properties is conducted to understand the source of the multi-contrast MPI channel leakage.

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610: Medicine, Health

620: Engineering

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https://creativecommons.org/licenses/by/4.0/

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IJMPI-Vol10-Iss1Suppl1-761.pdf

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