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Automated microfluidic system with optical set up for the investigation of peptide-antibody-interactions in an array format
Publikationstyp
Conference Paper
Date Issued
2015-10
Sprache
English
Author(s)
Weber, L. K.
Fischer, A.
Soehindrijo, M.
Förtsch, T. C.
Bojničić-Kninski, C.
Althuon, D.
Schillo, S. M.
Striffler, J.
Hubbuch, J.
Nesterov-Müller, A.
Start Page
120
End Page
122
Citation
MikroSystemTechnik Kongress 2015
Contribution to Conference
Scopus ID
Publisher
VDE-Verl.
ISBN
978-3-8007-4100-7
Peptide arrays are an ideal tool for the investigation of antibody-protein interactions. Several thousands of peptides can be screened simultaneously with a minimum of sample volume. Besides the information, if an antibody binds specifically to a peptide, it is of interest in which manner the antibody binds in terms of affinity. Therefor we developed a microfluidic system for the automated incubation of peptide arrays with biological samples. With an optical setup we can characterize the interaction of antibodies and peptides via fluorescence detection.
DDC Class
600: Technology