Mechanical behavior of screws in normal and osteoporotic bone

Publikationstyp
Conference Paper
Publikationsdatum
2005-12-01
Sprache
English
Author
Seebeck, Jannes 
Molekulardynamische Simulation weicher Materie M-EXK2 
Goldhahn, J.
Morlock, Michael 
Biomechanik M-3 
Schneider, E.
TORE-URI
https://hdl.handle.net/11420/46639
Enthalten in
Osteoporosis international 
Volume
16
Issue
SUPPL. 2
Citation
Osteoporosis International 16 (2): 107-111 (2005)
Publisher DOI
10.1007/s00198-004-1777-0
Scopus ID
2-s2.0-26944498694
Publisher
Springer
Fracture fixation in severe osteoporotic bone by means of implants that rely on screw anchorage is still a clinical problem. So far, a sufficiently accurate prediction of the holding capacity of screws as a function of local bone morphology has not been obtained. In this study the ultimate pullout loads of screws in the epi-, meta-, and diaphyseal regions of human tibiae were correlated to the cortical thicknesses and cancellous bone mineral densities at the screw axes determined from QCT densitometric data. Stepwise multiple linear regression showed that in regions with cortical thicknesses below 1.5 mm, cancellous density determined the ultimate pullout load (R2=0.85, p<0.001), while in regions with cortices above 1.5 mm, cortical thickness alone significantly influenced the holding capacity of a screw (R2=0.90, p<0.001). The findings of this study provide a basis for a bone morphology-related pre-operative estimation of the holding capacity of screws, which could help to improve their proper application in osteoporotic bone. © 2004 International Osteoporosis Foundation and National Osteoporosis Foundation.
Schlagworte
Bone morphology
Osteoporosis
Screw anchorage
DDC Class
610: Medicine, Health
620: Engineering