In vitro biocompatibility study and electrical properties of the PEDOT, PEDOT collagen coat, PEDOT nanotubes and PEDOT aerogels for neural electrodes

Start Page
320
End Page
326
Citation
Proceedings of the 10th IASTED International Conference on Biomedical Engineering : February 11 - 13, 2013, Innsbruck, Austria / ed.: A. R. Boccaccini. - Anaheim, Calif. [u.a.] : ACTA Press, 2013. - Seite 320-326
Contribution to Conference
10th IASTED International Conference on Biomedical Engineering, BioMed 2013 
Publisher DOI
10.2316/P.2013.791-072
Scopus ID
2-s2.0-84883882818
Publisher
ACTA Press
The aim of this study is to evaluate the cytotoxicity of Poly(3, 4-ethylenedioxythiophene) (PEDOT), PEDOT-collagen and PEDOT nanostructured coatings for neural electrodes. Incorporation of cell growth factors and the structuration of supporting material are two strategies to improve cell adhesion and biocompatibility in order to produce better and more specific neural implants. PEDOT coat, PEDOT-collagen coat, PEDOT nanotubes and PEDOT aerogel were tested for biocompability using the standard ISO 10993-5. PEDOT and PEDOT-Collagen coats were deposited via galvanostatic electropolymerization from a NaPSS micellar dispersion. In addition PEDOT nanotubes were obtained by hard polycarbonate template and PEDOT aerogels were chemically produced through a soft starch template. PEDOT samples were studied for biocompatibility, characterized by LCRmeter and Scanning electron microscopy (SEM). Biocompatibility test verified the absence of cytotoxic effects in all the PEDOT samples.
Schlagworte
Aerogels
Bio-nanotechnology
Biocompatibility
Nanotubes
Neural engineering
PEDOT
Structuration
DDC Class
620: Ingenieurwissenschaften