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Active pneumatic microballoon mixing on centrifugal microfluidic platforms
Publikationstyp
Conference Paper
Date Issued
2020-01-01
Sprache
English
Author(s)
Aeinehvand, Mohammad Mahdi
Perebikovsky, Alexandra
Carvajal, Agustín E.
Korvink, Jan G.
Madou, Marc
Martínez-Chapa, Sergio O.
Start Page
259
End Page
260
Citation
21st International Conference on Miniaturized Systems for Chemistry and Life Sciences Microtas, (MicroTAS 2017)
Scopus ID
ISBN
978-0-6929-4183-6
In this study, we are introducing an liquid reciprocation technique on centrifugal microfluidic platforms based on active microballoons. The liquid reciprocation technique is tested for mixing 22 µl water with 3 µl color in a large-surface-area-to-volume-ratio chamber. The color homogenization within the shallow chamber was achieved in less than 5 seconds, during which about sixty liquid reciprocation cycles were accomplished. As an early proof of concept for using the active flow reciprocation mechanism and peptide microarrays in point of care (POC) diagnostics applications, we co-integrated both technologies in a microfluidic disc for detection of 15 nM anti-FLAG Cy5 antibodies.
Subjects
Centrifugal microfluidics
Multiplex immunoassay
Peptide microarray
Reciprocating flow
DDC Class
600: Technology